Clinical research on renal cancer

Research on renal cancers and the clinical service offered to patients is increasing, and it is now a major theme for the CRUK Cambridge Centre. The Centre offers a full range of clinical services for patients and, wherever possible, offers opportunities to patients to take part in clinical research.  We maintain a highly active clinical trials portfolio, recruiting around a third of patients into clinical trials. The centre runs internationally recognised programmes in the genetics of the disease and the metabolic consequences of those genetic abnormalities, in understanding tumour biology and in the treatment of resulting malignancies. 
 
Clinical trials on renal cancer
Clinical trials in renal cancer are assessing the development of tyrosine kinase inhibitors as therapeutic agents. 

Current open trials in Cambridge

Please download a list of current open trials for renal cancer coordinated by the Cambridge Cancer Trials Centre (last updated January 2016).

Trial name Trial description Contact
A-PREDICT A-PREDICT - A Phase II Study of Axitinib in Patients with Metastatic Renal Cell Cancer Unsuitable for Nephrectomy Prof Tim Eisen
Pazopanib in patients with renal cancer (PaZ02) A study of pazopanib efficacy and safety in patients with advanced clear-cell renal cell carcinoma and ECOG Performance Status 2 (PaZ02) Dr Kate Fife
STAR Standard vs Modified Drug Therapy in Renal Cancer STAR: A randomised multiStage phase II/III trial of Standard first-line therapy (sunitinib or pazopanib) comparing Temporary cessation with Allowing continuation, at the time of maximal radiological response, in the firstline treatment of locally advanced and/or metastatic Renal cancer Prof Tim Eisen
WO29637 - MPDL3280A in renal cell A phase III, open-label, randomized study of MPDL3280A (Anti-PD-L1 antibody) in combination with bevacizumab versus sunitinib in patients with untreated advanced renal cell carcinoma Dr Kate Fife

If you would like further information about how to take part in any of the clinical trials listed here that are open to recruitment, please talk to your cancer specialist as patients usually need to be referred by their doctor. 

Cambridge Cancer Trials Centre contact for renal cancer trials:  Professor Tim Eisen