Professor Douglas Easton
Professor Douglas Easton is pleased to consider applications from prospective PhD students.
My main research area is genetic susceptibility to cancer, with particular emphasis on breast and prostate cancer. I also have particular interests in the genetic epidemiology of BRCA1 and BRCA2, intermediate markers of cancer risk (such as breast density), and in the development of statistical methods. A recent focus of my group has been large-scale association studies to identify moderate risk cancer susceptibillity variants. We co-ordinate international consortia conducting association studies in breast (BCAC) and prostate cancer (PRACTICAL), and in BRCA1/2 carriers.
High-throughput genotyping DNA sequencing
Easton DF et al (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature. 447(7148): 1087-93 Eeles RA et al (2008) Identification of multiple novel prostate cancer susceptibility loci by a genome-wide association study. Nature Genet. 40(3):316-21 Antoniou et al (2008) Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet 82(4):937-48