Professor Douglas Easton

University position: Professor
Personal home page: http://www.srl.cam.ac.uk/genepi/index.html

PubMed journal articles - click here

Professor Douglas Easton is pleased to consider applications from prospective PhD students.

Research description

My main research area is genetic susceptibility to cancer, with particular emphasis on breast and prostate cancer. I also have particular interests in the genetic epidemiology of BRCA1 and BRCA2, intermediate markers of cancer risk (such as breast density), and in the development of statistical methods. A recent focus of my group has been large-scale association studies to identify moderate risk cancer susceptibillity variants. We co-ordinate international consortia conducting association studies in breast (BCAC) and prostate cancer (PRACTICAL), and in BRCA1/2 carriers.

Research Theme
Early detection and intervention
Research Programme
Genetic epidemiology and cancer risk
Population sciences and primary care
Research Cancer Type
Breast cancer
Prostate cancer
Methods and technologies
Bioinformatics
Epidemiology
Genomics
PCR
Public health
Statistical analysis
Tumour type interests
Breast
Melanoma
Ovary
Prostate
Testis
Uterus and unspecified
Keywords

High-throughput genotyping DNA sequencing


Key publications

Easton DF et al (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature. 447(7148): 1087-93 Eeles RA et al (2008) Identification of multiple novel prostate cancer susceptibility loci by a genome-wide association study. Nature Genet. 40(3):316-21 Antoniou et al (2008) Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet 82(4):937-48