Professor Paul Pharoah

University position: Professor
Personal home page: http://www.srl.cam.ac.uk/

PubMed journal articles - click here

Professor Paul Pharoah is pleased to consider applications from prospective PhD students.

Research description

I am interested in the architecture of genetic susceptibility to common cancers (primarily breast, ovarian and colorectal). I am also interested in understanding how germline genetic variation influences disease heterogeneity and heterogeneity in the clinical outcomes of cancer.

Research Theme
Early detection and intervention
Personalised cancer medicine
Research Programme
Genetic epidemiology and cancer risk
Population sciences and primary care
Research Cancer Type
Breast cancer
Ovarian cancer
Prostate cancer

Key publications

1. Bolton KL, Chenevix-Trench G, Goh C, Sadetzki S, Ramus SJ, Karlan BY, et al. Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. JAMA 2012;307(4):382-90. 2. Pharoah PD, Antoniou AC, Easton DF, Ponder BA. Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 2008;358(26):2796-803. 3. Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, et al. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet 2013;45(4):362-70.